Margaret (Smedile) O'Keefe, in her 102nd year, in Chelsea formerly of East Boston and Revere passed away on Thursday, November 1, 2018. Mother of the late Richard and John O'Keefe. Grandmother of Michael O'Keefe of CO and loving aunt of Philip Smedile of Roslindale, Robert Smedile of Haverhill and Ann Spada of Norfolk. Sister of the late Josephine Panico, Lena Mastrogiovanni, Michael Smedile and loving aunt to numerous nieces and nephews. Relatives and friends are invited to attend visiting hours on Thursday November 8, 2018 from 10-11 AM at the Joseph Russo Funeral Home 814 American Legion Hwy (near Cummins Hwy) Roslindale, followed by a Funeral Mass in Sacred Heart Lower Church Roslindale at 11:30 AM. Interment in St Michael Cemetery Roslindale.